MAXXTOL Injection

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Composition:
Each ml Contains: Tolfenamic Acid 40 mg

Pharmacology and Mechanism of Action

Tolfenamic Acid has produced analgesic and anti-inflammatory effects by inhibiting the
synthesis of prostaglandins. The enzyme inhibited by NSAIDs is the cyclooxygenase enzyme (COX). Tolfenamic Acid is a balanced COX-1/COX-2 inhibitor.

Indications: All painful inflammatory conditions associated with Musculoskeletal Disorders, Respiratory Tract Infections, Mammary Gland Infections, Urogenital Tract Infections and Postoperative care Follow-up to Maxtol Injection wherever prolonged treatment is required.

Precautionary Information
Contraindications and Precautions
Do not administer to animals prone to GI ulcers. Do not administer with other ulcerogenic drugs such as corticosteroids. The original labeling for animals suggests that duration is limited to 5-7 days.

Drug Interactions
Like other NSAIDs, ulcerogenic effects are potentiated when administered with corticosteroids. Tolfenamic Acid, like other NSAIDs, may interfere with the action of diuretics, such as furosemide, and angiotensin-converting enzyme (ACE) inhibitors.

Dosage: Cattle and Buffalo: by VM or IW Route: 4 mg/kg b.wt. as a single
dose or 2 mg/kg b.wt. to be repeated after 48 hrs.

Sheep and Goat: By VM
or lW Route: 2mg/kg b.wt. as a single dose. Pig: By /M Route: 2mg/kg
b.wt. as a single dose.

Horse: By W Route: 2mg/kg b.wt as a single dose.