INTRAUTERINE BOLUS WITH NITROFURAZONE, UREA & METRONIDAZOLE)
Each bolus contains:
Nitrofurazone BP: 60 mg
Urea: 5000 mg
Metronidazole IP: 1000 mg
Antibacterial and antiprotozoal drugs. Its action is specific for anaerobic bacteria
and protozoa. Resistance is rare. Metronidazole oral absorption is nearly complete in animals. Metronidazole benzoate is formulated for cats to improve palatability. the half-life of 5 hours.
Indications and Clinical Uses
Metronidazole is indicated to treat diarrhea and other intestinal problems caused by intestinal protozoa such as Giardia, Trichomonas, and Entamoeba.
Instructions for Use
The maximum dose that should be administered is 50-65 mg/kg per day in any species. Metronidazole is unpalatable and can produce a metallic taste.
Small Animal Dosage
• Anaerobes: 15 mg/kg q12h or 12 mg/kg q8h PO.
• Giardia: 12-15 mg/kg q12h for 8 days PO.
• Anaerobes: 10-25 mg/kg q24h PO.
• Giardia: 17 mg/kg (one-third tablet per cat) q24h for 8 days.
Large Animal Dosage
• Treatment of trichomoniasis (bulls): 75 mg/kg q12h IV for three doses.
For prevention or control of uterine infections associated with retained placenta, metritis, cervicitis and vaginitis
ADMINISTRATION AND DOSAGE
Using aseptic precautions, insert by hand two to four boluses into each of the affected and normal uterine horns. Based on severity, repeat treatment after 24 hours.