Xylaxin Injection


Xylaxin injection (2% Solution) contains Xylazine Hydrochloride 23.22 mg per ml.


Xylaxin injection is recommended for inducing sedation and analgesia in various ani­mals, for restraining of animals for routine observations, minor surgical interventions, immobilization of animals during transportation and transhipment or any similar func­tions. It can also be used as a preanaesthetic to general anaesthesia.



By intramuscular route. For horses intravenous.

Species Dose in mg.per Kg. Body weight Dose per average adult
Cattle 0.1 to 0.2 1.5 to 3.0 ml
Horses 1.0 to 2.0 25.0 to 50.0 ml
Dogs 1.0 to 2.0 0.75 to 1.5 ml
Cats 1.0 to 2.0 0.1 to 0.5 ml
Sheep 0.1 to 0.3 0.1 to 0.5 ml
Goats 0.05 to 0.5 0.1 to 0.75 ml
Camels 0.1 to 0.5 5.0 to 20.0 ml
Wild Deers 1.5 to 3.0 2.50 to 4.5 ml
Elephants 0.1 to 0.4 5.0 to 20.0 ml



Xylaxin should not be used in conjunction with tranquilizers or neuroleptic drugs. Ani­mals in the last term of pregnancy should not be given the drug as it may induce early parturition or abortion. Cats and dogs with oesophageal obstruction, intestinal torsion or hernia as well as animals with pulmonary disorders should not be injected with Xylaxin.


After administration of Xylaxin the animal should be left undisturbed as excitement may reduce the level of sedation. Accidental falls and injury to be avoided during the induction of sedation by keeping the animal under observation after the onset of se­dation. Caution is required while administering the drug in weak and debilitated ani­mals.


Xylaxin is well tolerated in most animals without any side effects. A brief rise in blood pressure may occur which gradually becomes normal. Sweating and urination in horses, liquid and soft faeces in cattle, emesis in cats and dogs are some of the effects. The drug is rapidly excreted from the body.


Yohimbine hydrochloride and 4-amino pyridine are the antidotes for Xylaxin.


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